Treating hair loss involves much more than hair transplantation. While a hair transplant is generally recommended once hair loss has progressed to the point where follicles cannot recover naturally, medical therapies can often help preserve existing hair, improve hair quality, or complement surgical treatment.
One of the most commonly prescribed treatments in hair restoration medicine is hair mesotherapy. This minimally invasive procedure is designed to help slow hair loss while improving hair thickness, density, and overall hair quality.
Following a comprehensive consultation, Dr. Espinosa Custodio may recommend mesotherapy as part of a personalized treatment plan. Depending on the patient’s medical history and clinical findings, blood tests may be requested beforehand to assess overall health and determine the most appropriate combination of active ingredients.
Hair mesotherapy consists of a customized blend of medications and nutrients administered directly into the scalp. The treatment may be delivered through multiple superficial microinjections (microneedling) into the upper dermis or by deeper injection techniques performed manually or with specialized injection devices. Both methods are effective, although deeper delivery systems may allow treatment of larger areas more efficiently.
At Instituto Médico del Prado, hair mesotherapy is designed to be as comfortable as possible. The formulations used are liposomal and alcohol-free, significantly reducing the burning or stinging sensation that can occur with conventional injectable preparations.
Components used in hair mesotherapy
The composition of each mesotherapy treatment is individualized and may include one or more of the following active ingredients:
- Dutasteride – Helps reduce the effects of dihydrotestosterone (DHT), slowing follicular miniaturization associated with androgenetic alopecia.
- Minoxidil – Stimulates hair growth and promotes thicker, fuller hair.
- Latanoprost – May improve hair thickness, length, and pigmentation in selected patients.
- Prostaquinone (Nigella sativa extract) – May help inhibit prostaglandin PGD2, a molecule believed to contribute to androgenetic alopecia.
- Silicon – A mineral involved in maintaining hair strength and structure, although it does not directly stop hair loss.
- Biotin – Supports healthy hair growth and contributes to normal follicle metabolism.
- Melatonin – Provides antioxidant support and may help protect hair follicles from oxidative stress.
- Cyproterone acetate – Used primarily in selected female patients with androgen-related hair loss because of its anti-androgenic effects.
- Bicalutamide – An anti-androgen medication that may improve hair thickness in carefully selected patients, particularly women.
Not every treatment includes all of these ingredients. Dr. Espinosa Custodio tailors each formulation according to the patient’s diagnosis, medical history, and therapeutic goals.
Another option is Platelet-Rich Plasma (PRP) mesotherapy, which uses concentrated platelets obtained from the patient’s own blood. Vitamin-based formulations may also be used, providing a more natural alternative depending on the clinical indication.
Frequently Asked Questions
Is every mesotherapy treatment personalized?
Yes. At Instituto Médico del Prado, every mesotherapy treatment is individually designed. In some cases, blood tests are performed before treatment so that Dr. Espinosa Custodio can evaluate relevant health parameters and prescribe the most appropriate combination of active ingredients following the diagnostic consultation.
Is hair mesotherapy painful?
Mesotherapy can cause some discomfort depending on the products used. However, at Instituto Médico del Prado, liposomal alcohol-free formulations are used, which significantly reduce pain and eliminate the burning sensation commonly associated with conventional injectable solutions. As a result, treatment is generally very well tolerated.
Can mesotherapy be performed without a hair transplant?
Yes. Hair mesotherapy can be prescribed independently of hair transplantation. Depending on the patient’s needs, it may be used as a standalone treatment, as preparation before surgery, or as part of the postoperative maintenance plan following a hair transplant.
ués del mismo o independientemente del mismo.
Dr. Espinosa Custodio works at Instituto Médico del Prado, his hair clinic in Madrid, and performs hair transplants in Mexico, twice a year. If you would like to make an appointment, you can contact us on +34 912 468 664, on WhatsApp +34 627 396 322 or on the contact page of our website. From Mexico you can contact us at +52 55 4590 9909.


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